Aug 5, 2018
Fluoroquinolones such as ciprofloxacin, moxifloxacin and ofloxacin have a distinctive profile of adverse effects. The US FDA has recently issued new warnings to highlight the risk of profound hypoglycaemia, as well as mental state changes including delirium. Coming in...
Aug 5, 2018
Acute kidney injury (AKI) is common after major vascular surgery. In a retrospective cohort study of hypertensive patients undergoing elective major vascular surgery researchers sought to determine if there was an association between the number of antihypertensive...
Aug 5, 2018
Korean researchers have conducted a randomised study of people with RA on stable dose of MTX who were randomly assigned continue MTX or to hold MTX for 2 weeks after quadrivalent seasonal influenza vaccination. The primary outcome was frequency of satisfactory vaccine...
Aug 5, 2018
In a large longitudinal study of 411 patients with early Parkinson’s disease, 356 (86.6%) were treated with a dopamine agonist at least once since the onset of their illness. In 306 patients who were known to have no evidence of an impulse control disorder (ICD...
Aug 5, 2018
In a recent study published in the CMJA, the evidence supporting the use of gabapentin, pregabalin and topiramate for low back pain and lumbar radicular pain. Based upon self-reported efficacy, disability and adverse effects, the evidence supporting the use of these...