Adverse effects of low dose methotrexate

Around the world, low-dose methotrexate (LD-MTX) is the medication most commonly for systemic rheumatic diseases and is the recommended first-line agent for rheumatoid arthritis. Little information is available to inform clinicians about the nature and prevalence of...

Involve older people in deprescribing discussions

A recent cross-sectional survey has assessed the attitudes of patients and caregivers regarding deprescribing. Conducted in Singapore, the study involved 615 older adults and 442 caregivers and aimed to link the individual’s characteristics with beliefs on medication...

Aspirin for VTE prophylaxis after arthroplasty

Some observational data suggest aspirin might afford effective VTE prophylaxis. A systematic review and meta-analysis of randomized clinical trials (RCTs) has recently examined the issue. RCTs assessing the effectiveness and safety of aspirin for VTE prophylaxis...