Ketamine for depression

There has been considerable interest in the potential clinical efficacy of ketamine for the management of depression, albeit there is also concern about the durability of benefit and potential adverse effects, especially in the longer term. Read more in excellent...

What is the best treatment option for recurrent C Difficile infection?

In a small prospective clinical trial, researchers randomly assigned people with recurrent C Diff infection to receive fecal microbiota transplantation (FMT), applied by colonoscopy or nasojejunal tube after 4–10 days of vancomycin (125 mg 4 times daily, comparing...

Penicillin allergy primer

β-Lactam antibiotics are wide used for a reason – they are safe and effective antibiotics. Recent reports of issues with other drugs have served to emphasize this, for example the multiplicity of issues associated with flouroquinolones that has been prominent in...

VTE and HRT – not all products are equal

Using nested case-control studies, British researches have explored the association between risk of venous thromboembolism and use of different types of hormone replacement therapy. 80 396 women aged 40-79 with a primary diagnosis of venous thromboembolism were...