Veterans MATES – Update on PPIs

The Veterans MATES service provides high-quality periodic updates in Therapeutic Briefs addressing important topics relevant to the safe and effective use of medicines – read the latest update update dealing with the Proton Pump Inhibitors...

Concerns about gabapentinoid abuse potential grows

Concern continues to evolve over the potential for abuse of gabapentinoid drugs (gabapentin, topiramate, and most notably, pregabalin). One reason underpinning this concern is the observations that 1) euphoria and dissociation seem to be dose-dependent adverse effects...

Probiotics fail to deliver for children with gastroenteritis

Acute gastroenteritis is a common reason for emergency department visits amongst young children. Although advocated vigorously by some, probiotics have not been properly assessed as regards their propensity to improve outcomes in childhood gastroenteritis. A recent...

Inappropriate prescribing may begin in hospital

It is well-known that older people are the most extensive users of prescribed medications, albeit for many reasons this sub-population is at greatest risk for medication-related problems. Although a great deal of medication prescribing in primary care is repeat...