Oct 30, 2019
The Hygia Chronotherapy Trial, recently conducted in Spain, has assessed the effect of the timing of hypertension therapy upon cardiovascular disease (CVD) risk reduction. The multi-centre, controlled, prospective trial included 19,084 hypertensive patients (mean age...
Oct 29, 2019
Researchers have recently assessed the specificity of an algorithm to detect look-alike/sound-alike (LASA) medication prescribing errors in electronic health record (EHR) data: data derived from eight years of medication orders and diagnostic claims were analysed. The...
Oct 28, 2019
A systematic review and meta-analysis recently published by the American College of Chest Physicians has assessed the effects of vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs) during extended anticoagulation for VTE events, addressing both overall...
Oct 24, 2019
While herpes zoster (HZ) has been linked to JAK inhibitors such as tofacitinib, it is unclear whether concomitant methotrexate (MTX) and/or glucocorticoids increase this risk. In a recent American study, HZ risk has been assessed in tofacitinib-treated rheumatoid...
Oct 24, 2019
Commonly prescribed drugs appear to have an important impact on the gut microbiome. Researchers from the Netherlands reported that 18 common drug classes appear to have been associated with alterations in gut flora profiles. The research involved metagenomic...
