Evidence presented at a major American conference suggests that the extent of virological suppression achievable with long-acting injectable antiviral products appears to be similr to that attained using daily oral treatment with highly active antiretroviral...
From a a large study involving 6539 people, two big propensity score–matched cohorts of 1844 patients were analyzed (those receiving warfarin + aspirin vs those on warfarin only). After a year, patients receiving the combination had higher rates of overall bleeding...
Danish researchers have used 5 025 754 person-years of follow-up to address a long-standing matter of what has been an issue of contention: during the follow-up, 6517 children were diagnosed with autism, at an incidence rate, 129.7 per 100 000 person-years. Comparing...
In the medicines safety community, one would need to be living under a rock not to have read a great deal about deprescribing by now. Less attention has been devoted to diagnoses, which allow clinicians to make sensible prescribing decisions. In a new slant, the...
Both tramadol and codeine are CYP2D6 substrates. A recent study has shown that people who are ultrarapid and poor CYP2D6 metabolizers are less liekly normal or indeterminate metabolizers (p = 0.01). After adjusting the CYP2D6 activity score for drug–drug interactions,...
