Gender differences in heart failure treatment outcomes

New research published in The Lancet has examined the gender-differential effects of the doses of angiotensin-converting-enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) and β blockers when used for heart failure with reduced ejection fraction (HFrEF)....

Genomic predisposition to poorer outcomes with clopidogrel

The link between the AKR1D1*36 (rs1872930) allele and risk of major adverse cardiovascular and cerebrovascular events (MACCE) in patients taking clopidogrel has been examined in a recent observational pharmacogenomic cohort study. 118 patients (median age 62.5 years)...

Alzheimer’s and adverse drug reactions

The increasing incidence of Alzheimer’s disease has seen an accompanying increase in adverse drug events (ADEs) related to various psychotropic medications used by these patients. To assess the prevalence and economic burden of psychotropic ADEs, American...