In particular for older people, declining renal function poses an important clinical consideration with respect to the possibility of continuing treatment with angiotensin-converting enzyme inhibitor (ACE-I) and angiotensin II receptor blocker (ARB) treatment in the...
Medications are a major and modifiable risk factor for falls. A recent systematic review and meta-analysis examined the associations between cardiovascular medications and fall risk in older adults.131 studies were included, revealing increased risk with loop...
The clinical outcomes of deprescribing interventions among residents in nursing homes are not well understood and has recently been evaluated in a systematic review and meta-analysis of randomized controlled trials in an aged care setting including people 60 years of...
Use of macrolide antibiotics during pregnancy increases the risk for miscarriage. A large population based cohort study in the UK has assessing 104,605 children born from 1990-2016 with mothers prescribed with either one macrolide or one penicillin monotherapy during...
The association between gastric acid suppressants and risk of intestinal colonisation with multidrug-resistant microorganisms (MDROs) has been investigated by a team of researchers in the Netherlands. The systematic review and meta-analysis of 26 observational studies...
