May 22, 2020
Potentially inappropriate medications (PIMs) pose greater risk of harm than benefit, especially when prescribed for patients aged 65 years and over. Hospitalisation provides an opportunity for medication review – while some PIMs are deprescribed or replaced...
May 20, 2020
A new retrospective analysis of the incidence, type and risk factors associated with adverse drug reactions (ADRs) in COVID-19 patients has been published from China. The study used active monitoring of the China Hospital Pharmacovigilance System (CHPS) to detect ADR...
May 19, 2020
A novel rifabutin-based treatment (RHB-105) for Helicobacter pylori infection has been examined in a double-blind, randomised, controlled trial in the United States. The study involved 455 patients with epigastric discomfort and confirmed H pylori infection, who...
May 17, 2020
A clinically significant drug interaction between antidepressants and beta-blockers has been examined in research from in the United States. The inhibition of the CYP2D6 hepatic isoenzyme by various antidepressants can result in increased plasma concentrations of...
May 14, 2020
A longitudinal cohort study has investigated how the ability of older adults to correctly interpret, dose and organise standardised multi-drug regimens changes over time. The study commenced in 2008 and included 900 people aged 55-74 years. At baseline (T1),...
May 11, 2020
Researchers in the United States have evaluated the association between deprescribing acetylcholinesterase inhibitors (AChEIs) and all-cause negative events such as hospitalisation, emergency department visits and mortality, as well as serious falls or fractures, in...
