VTE risk after antipsychotic drug use

There is conjecture regarding a possible association between use of antipsychotic drugs and the development of venous thromboembolism (VTE). Researchers from the USA recently published research that compared the incidence of antipsychotic use in patients who developed...

Polypharmacy on the rise amongst older Australians

Australian researchers have recently published data on an estimate of the prevalence of polypharmacy among Australians aged 70 years or more, spanning the years 2006–2017. Using data from a random 10% sample of Pharmaceutical Benefits Scheme (PBS) – the...

Benefits of antiviral treatment for confirmed influenza

Recent research published in The Lancet has shone a light on the potential benefits of adding antiviral treatment to usual primary care for patients with influenza-like illness, seeking to determine if this approach reduces time to recovery overall, and for people in...

NSAIDs further increase bleeding risk with anticoagulation

Concurrent use of NSAIDs with oral anticoagulants has conventionally been thought to confer an increased risk of bleeding, but data from the recently reported ARISTOTLE trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation;...

FDA issues gabapentinoid warning statement

The US FDA have issued a warning about the risks of co-prescribing gabapentinoids with other respiratory depressants. An extract from the statement: Health care professionals should start gabapentinoids at the lowest dose and monitor patients for symptoms of...

Testosterone supplementation increases risk of VTE

A case-crossover study conducted in the USA has investigated the relationship between testosterone therapy and short-term risk of venous thromboembolism (VTE) in men with and without hypogonadism. The study spanned across January 2011 to December 2017 and included...