May 19, 2019
Researchers in the USA have used claims data to assess the risk of persistent opioid use after hospital discharge for patients treated with tramadol alone compared with other short acting opioids. The research used three commonly used definitions of prolonged opioid...
May 17, 2019
A large study of 442 066 pregnancies included in the Quebec Pregnancy Cohort, found that in 27 149 cases (6.1%) the outcome was spontaneous abortion, and amongst these women 375 (1.4%) were exposed to benzodiazepines in early pregnancy compared with 788 (0.6%) of...
May 15, 2019
Post-partum sepsis is thought to cause 11% of maternal deaths globally and in 2016, it is estimated that 19 500 women died because of pregnancy-related infections. Antibiotic prophylaxis at caesarean section is widely recommended because it reduces incidence of...
May 14, 2019
In Australia, the opioid antagonist naloxone can be supplied directly from a pharmacist to patients without the need for a prescription (a Schedule 3 medicine). This scheduling change has been implemented with the intention of reducing opioid-related mortality arising...
May 13, 2019
The Australian Prescriber has published an excellent review of acute drug-induced hyperthermia – see more here
May 13, 2019
There is increasing attention focused upon cannabidiol (CBD), a non‐psychoactive derivative from cannabis that is advocated for various therapeutic uses. CBD undergoes metabolism via the CYP3A4 and CYP2C19 isoenzymes, and it appears that the compound may also be a...
