Mar 10, 2019
From a a large study involving 6539 people, two big propensity score–matched cohorts of 1844 patients were analyzed (those receiving warfarin + aspirin vs those on warfarin only). After a year, patients receiving the combination had higher rates of overall bleeding...
Mar 10, 2019
Danish researchers have used 5 025 754 person-years of follow-up to address a long-standing matter of what has been an issue of contention: during the follow-up, 6517 children were diagnosed with autism, at an incidence rate, 129.7 per 100 000 person-years. Comparing...
Mar 10, 2019
In the medicines safety community, one would need to be living under a rock not to have read a great deal about deprescribing by now. Less attention has been devoted to diagnoses, which allow clinicians to make sensible prescribing decisions. In a new slant, the...
Mar 8, 2019
Both tramadol and codeine are CYP2D6 substrates. A recent study has shown that people who are ultrarapid and poor CYP2D6 metabolizers are less liekly normal or indeterminate metabolizers (p = 0.01). After adjusting the CYP2D6 activity score for drug–drug interactions,...
Mar 8, 2019
Polypharmacy is often a finding at the end of life. A recent study of adults with advanced, life-limiting illness examined the possible effects of this syndrome upon symptom burden (assessed using the Edmonton Symptom Assessment Scale) and quality of life (assessed...
Mar 8, 2019
Statin treatment is implemented to decrease mortality amongst people with atherosclerotic cardiovascular disease. Researchers have recently used a very large cohort study to explore the association between statin adherence and mortality in these patients. The primary...
