QT prolongation and cholinesterase inhibitors

Acetylcholinesterase inhibitors (AChEis) include donepezil, galantamine and rivastigmine, and are used to manage cognitive decline associated with advancing dementia. A recent study evaluated evidence from case reports literature seeking to determine if there is an...

Risk of major GI bleeding in older patients taking aspirin

The ‘ASPirin in Reducing Events in the Elderly’, or ‘ASPREE’ study, was a randomised, controlled trial of aspirin versus placebo for prevention of CV events, between 2010-2017 by a team of researchers from Australia and the United States. Its aim was to address the...