Nov 16, 2018
Gabapentinoids (gabapentin and pregabalin) are widely prescribed for older people. Case reports have previously documented an association with Atrial Fibrillation, and Spanish researchers have explored this potential relationship further. Older patients without...
Nov 16, 2018
Sodium glucose cotransporter 2 (SGLT2) inhibitors are now an established option for treatment of type 2 diabetes, but there has been concern the possibility that these agents are associated with higher rates of lower limb amputation, as well as various other uncommon...
Nov 14, 2018
In a study from the USA recently published in the New England Journal of Medicine, researchers used randomized, placebo-controlled trial, to assess the effects of cholecalciferol at a dose of 2000 IU per day and fish oil (omega-3 fatty acids) 1000 mg per day for the...
Nov 11, 2018
Off-label use of medicines is thought to contribute to preventable adverse drug events (ADEs) in children. A recent study published by the JAMA network has examined this issue in a population of over 46,000 adults who were treated with 151 305 incident prescribed...
Nov 11, 2018
Considering how widely the third generation cephalosporin ceftriaxone is prescribed, it is fortunate that this haemolytic anaemia is a relatively rare adverse effect. Nevertheless, clinicians need to be aware of this issue, and a recent case report and literature...
Nov 10, 2018
Derivatives Mitragyna speciosa, also known as kratom, are becoming an increasing focus of attention. The herbal preparation of this plant (indigenous to SE Asia) is growing in popularity in North America and is now being advocated as a treatment for pain and for...