Gabapentinoids and AF in the elderly – a further issue for concern

Gabapentinoids (gabapentin and pregabalin) are widely prescribed for older people. Case reports have previously documented an association with Atrial Fibrillation, and Spanish researchers have explored this potential relationship further. Older patients without...

What Vitamin D and Fish Oil did not do …

In a study from the USA recently published in the New England Journal of Medicine, researchers used randomized, placebo-controlled trial, to assess the effects of cholecalciferol at a dose of 2000 IU per day and fish oil (omega-3 fatty acids) 1000 mg per day for the...

Ceftriaxone & haemolytic anaemia – an uncommon but important effect

Considering how widely the third generation cephalosporin ceftriaxone is prescribed, it is fortunate that this haemolytic anaemia is a relatively rare adverse effect. Nevertheless, clinicians need to be aware of this issue, and a recent case report and literature...

Kratom – what’s the big deal?

Derivatives Mitragyna speciosa, also known as kratom, are becoming an increasing focus of attention. The herbal preparation of this plant (indigenous to SE Asia) is growing in popularity in North America and is now being advocated as a treatment for pain and for...