A great deal has been written about how older people who take PPIs for long periods of time may be susceptible to adverse events. A team of Australian pharmacist and nurse researchers has just published a study that examined the use of PPIs in residential aged care facilities. 383 residents in six facilities were studied, with 196 (51%) treated with a PPI, 45 (23%) of whom were prescribed a high dose. The majority – 173 (88%), had documented clinical indications or received medications that can increase bleeding risk. Three-quarters of PPI users with gastroesophageal reflux disease or dyspepsia had received a PPI for > 8 weeks. Although it is always worthwhile reviewing the continuing need for treatment and considering “step-down” approaches for high-dose PPI users, this research suggests that the drugs are not prescribed without regard to clinical indications. Read more here
There may be good reasons for the use of PPIs amongst older people in aged facilities
Jul 2, 2019