Adverse drug reactions and hospitalisation – an Italian perspective

Researchers from Italy have recently published a study examining the role of ADRs in contributing to hospitalization of the elderly. The study was used a retrospective observational design that analysed the admissions of every patient aged over 65 years of age...

Physician education, academic detailing successfully reduces opioid use

Education works! A multilevel campaign that included departmental grand rounds, data review, circulation of journal papers that highlight the effects of opioid over-prescribing, visual display of individual clinician prescribing for comparison with peers, and academic...

Increased falls and ED visits with combined benzodiazepines + opioids

New evidence sheds additional light on the risks inherent to combined opioid/benzodiazepine treatment. In a cross-sectional study of 517 adults with musculoskeletal pain and current prescriptions for long-term opioid therapy, 25% had concurrent benzodiazepine and...

Increasing awareness of antidepressant discontinuation syndrome

An excellent international review of antidepressant discontinuation syndrome has recently been published in the the journal Addictive Behaviours.  The authors conclude that “guidelines on antidepressant withdrawal [should] be urgently updated as they are clearly...