Nov 21, 2018
In the USA, the Pediatric Research Equity Act of 2003 means that the US FDA can require sponsor pharmaceutical companies to conduct specifif pediatric clinical studies, in order that the approved product information can incorporate proper prescribing guidance for...
Nov 20, 2018
In 2015 the American Geriatrics Society promulgated an updated version of the “Beers Criteria” list of drugs to avoid in older adults, drugs that are unsuited for use in the older person because of the risk of harm and availability of safer treatments....
Nov 16, 2018
Gabapentinoids (gabapentin and pregabalin) are widely prescribed for older people. Case reports have previously documented an association with Atrial Fibrillation, and Spanish researchers have explored this potential relationship further. Older patients without...
Nov 16, 2018
Sodium glucose cotransporter 2 (SGLT2) inhibitors are now an established option for treatment of type 2 diabetes, but there has been concern the possibility that these agents are associated with higher rates of lower limb amputation, as well as various other uncommon...
Nov 14, 2018
In a study from the USA recently published in the New England Journal of Medicine, researchers used randomized, placebo-controlled trial, to assess the effects of cholecalciferol at a dose of 2000 IU per day and fish oil (omega-3 fatty acids) 1000 mg per day for the...