Off-label use of medicines is thought to contribute to preventable adverse drug events (ADEs) in children. A recent study published by the JAMA network has examined this issue in a population of over 46,000 adults who were treated with 151 305 incident prescribed...
Considering how widely the third generation cephalosporin ceftriaxone is prescribed, it is fortunate that this haemolytic anaemia is a relatively rare adverse effect. Nevertheless, clinicians need to be aware of this issue, and a recent case report and literature...
Derivatives Mitragyna speciosa, also known as kratom, are becoming an increasing focus of attention. The herbal preparation of this plant (indigenous to SE Asia) is growing in popularity in North America and is now being advocated as a treatment for pain and for...
Patients undergoing surgery appear to be prescribed more opioids than are needed, using only 27% of the drugs prescribed from them. In a recent study from the USA, the number of dosage units had the strongest association with opioid consumption after surgery, with...
Despite the opioid crisis that it current in the USA, the FDA has recently approved a sublingual dosage form of sufentanyl, a drug with opioid effects an order of magnitude more powerful than fentanyl, which itself is implicated in many opioid-related deaths. Intended...
