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Apixaban with a P2Y12 inhibitor outperforms other approaches for those with AF and recent acute coronary syndrome or PCI

Mar 21, 2019

How to choose antithrombotic therapy for patients with atrial fibrillation and who have an acute coronary syndrome or have undergone percutaneous coronary intervention (PCI)? Oral anticoagulation needed to prevent stroke with AF, but this approach doesn’t stop...

Brexanolone approved for treatment of postpartum depression: effective, but costly

Mar 21, 2019

The US FDA have approved brexanolone intravenous injection for treatment of postpartum depression. The proposition is that the drug will be available through a restricted programme administered by the sponsor, Sage Therapeutics. Brexanolone is administered as a...

Pharmacist-led AMS reduces both inappropriate antibiotic allergy labeling & prescribing of restricted antibiotics

Mar 19, 2019

Antibiotic allergies are reported on labels for up to 25% of hospitalized patients, but can compromise appropriate prescribing. In recent Australian research, a pharmacist-led penicillin allergy de-labeling ward round examined hospital inpatients with a documented...

New guidelines for VTE investigation and management issued by Thrombosis and Haemostasis Society of Australia and New Zealand

Mar 19, 2019

The Thrombosis and Haemostasis Society of Australia and New Zealand have recently issued new guidance for the diagnosis and management of venous thromboembolism. The comprehensive document is a valuable resource that provides guidance for clinicians in specific areas...

Tramadol may be less safe than NSAIDs for management of knee pain in OA

Mar 14, 2019

The American Academy of Orthopaedic Surgeons has recommended the use of tramadol for the management of pain for patients with knee osteoarthritis, and the American College of Rheumatology guideline also conditionally recommends tramadol as first-line therapy for...
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