Bleeding risk & various oral anticoagulants in AF 

A study recently published in the American Journal of Cardiology has explored the bleeding risk associated with oral anticoagulants (OACs) in patients with atrial fibrillation. Although direct oral anticoagulants (DOACs) have a favourable bleeding safety profile in...

Older patients with AF have a higher risk of major bleeding

The safety of direct oral anticoagulants in patients with atrial fibrillation and aged ≥ 85 years has been evaluated in a prospective Slovenian study. There were 2,260 patients with atrial fibrillation aged ≥ 65, who received dabigatran, rivaroxaban or apixaban...

H pylori eradication and C difficile super-infection

Treatment and eradication of Helicobacter pylori (HP) infection is recommended due to its association with numerous gastrointestinal pathologies, it has been speculated that HP treatment could increase the risk of Clostridium difficile infection (CDI). An American...

Clinical pharmacists protect children from medication errors

Clinical pharmacy services are believed to reduce medication errors. Children are vulnerable to medication errors due to various factors. In a recent meta analysis, researchers undertook a qualitative and quantitative evaluation of the impact of clinical pharmacist...

Apixaban outperformed rivaroxaban for AF

Commonly prescribed direct oral anticoagulants for patients with non-valvular atrial fibrillation include apixaban and rivaroxaban, but there is a lack of compelling evidence to allow comparison of the two drugs. A recent retrospective cohort study has examined the...