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Older people with dementia more commonly prescribed inappropriate medications

Sep 29, 2020

Using a retrospective cohort study design, British researchers have recently investigated the nature of drug treatment amongst people with dementia, specifically looking at evidence for potentially inappropriate prescribing (PIP). Data were derived primary care...

OECD report highlights gigantic economic burden of safety and quality issues in long term care

Sep 29, 2020

The OECD has recently estimated that the total cost of avoidable admissions to hospitals from Long Term Care (LTC facilities) in 2016 was in the order of $USD18, equivalent to 2.5% of all spending on hospital inpatient care, and is set to increase by about 20% in the...

Confirmation that daily steroid treatment for RA increases risk of serious infections

Sep 29, 2020

Low-dose steroids are commonly used for the management of rheumatoid arthritis (RA), despite the fact that these agents are commonly associated with serious adverse effects including significant infections. A recently published retrospective cohort study has assessed...

Assessment of NDAs for opioids for chronic pain – how searching are the criteria used for assessment?

Sep 29, 2020

An analysis recently published in The Annals of Internal Medicine has found that most of the 48 New Drug Applications (NDAs) for opioid analgesics approved by the FDA between 1997 and 2018 assessed new dosage forms (n = 25 [52.1%]) or new formulations (n = 9 [18.8%]);...

Drug-drug interaction reports generated by computers – just how valuable are they?

Sep 29, 2020

Australian researchers have recently examined the different types of adverse drug events (ADEs) that drug-drug interaction (DDI) alerts are configured to prevent in hospitalized patients. Using a retrospective cross-sectional design, the investigators analysed all DDI...
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