Jan 8, 2019
Broadening of the QT interval on ECG is a serious issue, and may result in life-threatening torsade de pointes. Australian researchers have recently examined the use of QT interval-prolonging drugs amongst elderly people undergoing medication reviews. 500 medication...
Jan 8, 2019
In 2007 the American Heart Association updated its recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE). The significant change was that AP should not be offered for those at moderate risk of IE. Examination of a large health claims...
Jan 6, 2019
Another serious adverse effect associated with fluoroquinolone use – this time the FDA has issued a warning about an apparent increase in the prevalence of ruptured aortic aneurysm, a rare but catastrophic event. More information here
Jan 5, 2019
Ondansetron usually considered as a first-line agent for nausea in emergency departments, but may not work as well for people without a cancer diagnoisis. A recent study examined 120 adult ED patients with nausea or vomiting who did not require intravenous access,...
Jan 5, 2019
In a large observational study from Sweden involving over 200,000 people aged 65 years or older who had a prescription of antidepressants filled , matched by birth year and sex to 1 control participant not prescribed antidepressants, incident hip fractures occurring...
Jan 5, 2019
For people with dilated cardiomyopathy whose symptoms and cardiac function have recovered, there has been some degree of doubt as to the best approach to drug treatment. British researchers have now completed a randomised trial to examine the effect of phased...
