Allopurinol and kidney function – don’t panic!

What to do about allopurinol in renal impairment? A question that has taxed clinicians  for many years. In a new study published in JAMA Internal Medicine, researchers have suggested that this drug may be less fraught for these patients than previously thought. People...

A Canadian reminder about unsafe medication abbreviations

The Institute for Safe Medication Practices Canada has issued a reminder about potentially unsafe medication abbreviations. Reading the document, it is clear that there are many ways for some commonly encountered abbreviations to be misinterpreted with potentially...

Europeans recommendation restrictions on fluouroquinolone use

The European Medicines Agency (EMA) has recommended restrictions on the use of fluoroquinolone and quinolone antibiotics in view of the association of these medications with adverse effects involving muscles, tendons and bones and the nervous system. The...

Adverse drug reactions and hospitalisation – an Italian perspective

Researchers from Italy have recently published a study examining the role of ADRs in contributing to hospitalization of the elderly. The study was used a retrospective observational design that analysed the admissions of every patient aged over 65 years of age...

Physician education, academic detailing successfully reduces opioid use

Education works! A multilevel campaign that included departmental grand rounds, data review, circulation of journal papers that highlight the effects of opioid over-prescribing, visual display of individual clinician prescribing for comparison with peers, and academic...