There has been a dearth of options available to clinicians when it comes to the pharmacological management of methamphetamine use disorder. On this background, a group from the USA have conducted a multisite, double-blind, two-stage, placebo-controlled trial with the...
Recently published research from Italy was conducted to describe the characteristics of adverse drug events (ADEs) with a fatal outcome encountered in the ED setting, including the drugs involved, the frequency of the events and an estimate of the preventability of...
Remdesivir has been the focus of much attention in the context of the COVID-19 pandemic. A recent examination of the WHO VigiBase® has focused on Adverse Drug Events (ADEs) amongst COVID-19 patients. 1086 ADEs were reported from the 439 individual case reports up to...
Bisphosphonates are widely used because of their effectiveness in reducing hip and osteoporotic fractures, but there have been concerns about atypical femur fractures. In study of women 50 years of age or older who were receiving bisphosphonates, researchers examined...
The merits and drawbacks of so-called “polypills” continue to be debated. Researchers have recently assessed the effects of this approach using a multi-component strategy that included a statin, antihypertensives and aspirin to reduce the risk of...
The prevalence, severity and type of preventable medication harm in a medical care setting has been quantified in a systematic review and meta-analysis recently conducted by researchers in the United Kingdom. From 81 studies involving 285,687 patients, the pooled...